Our Technology
Volta is building a sequencer agnostic front-end platform.
Reduce hands on time and operator training burden with push button protocols that use a simple consumable.
Overview
Digital Fluidics, a precision tool for biological sample manipulation.
How it Works
Step 1: Sample Input
Cell lysates are loaded onto the platform.
Whole blood
Buffy coat
PMBCs
Cell cultures
Tissues
Step 2: Nucleic Acid Extraction
Automated bead-based extraction is performed to produce purified nucleic acids (including RNA and HMW DNA).
Step 3: Optional Stopping Point
For flexibility, an optional stopping point is created to enable for Q.C., cDNA synthesis, and/or mechanical shearing steps.
cDNA Synthesis
QC
Mechanical Shearing
Step 4: Library Preparation
Input DNA and library prep reagents are loaded to perform steps associated with end repair, ligation, tagmentation, and bead clean-up.
Bead Clean-up
Mixing Reagents
Loading Reagents
Features
Flexible. Scalable. Accessible.
“Push button” sample prep workflow
One Digital Fluidics platform, multiple nucleic acid extraction and library prep applications.
HMW DNA extraction
Universally compatible with short and long read sequencing technologies.
Oxford Nanopore Technologies library prep
Robust library conversion efficiency and nanopore occupancy.
Illumina SBS library prep
PCR-free library prep for whole genome sequencing.
PacBio HiFi library prep
Significant reduction of hands-on time and pipette tip consumption.
Element AVITI™ library prep
Libraries produced and circularized using Adept are high yield and generate good coverage across the genome with no GC bias.
